Searchable abstracts of presentations at key conferences in endocrinology

ea0081p718 | Thyroid | ECE2022

Clinical presentation and significance of thyroid dysfunctions secondary to PD-1/PD-L1 blockade cancer immunotherapy

Di Dalmazi Giulia , Elena Sorbo Sofia , Dudiez Andrea , Ciappini Beatrice , Cipolloni Ilaria , Russo Gianluca , Luisi Dimitri , Napolitano Giorgio , Bucci Ines

Background: Thyroid dysfunctions are among the most common immune-related adverse events (irAEs) following the administration of immune checkpoint inhibitors (ICIs) for malignancies. The pathogenesis of thyroid irAEs remains unclear and the clinical course can be multifaceted.Aim: Aims of this study were a) to describe the incidence and the clinical course of thyroid irAEs b) to determine the association between thyroid irAEs and overall survival (OS).</...

ea0081p719 | Thyroid | ECE2022

Serum FT3 levels and FT3/FT4 ratio as predictors for poor prognosis in hospitalized COVID-19 patients

Milo Marica , Di Dalmazi Giulia , Febo Fabrizio , Coluzzi Sara , Carrieri Federica , Terrenzio Marco , Ferrandu Giovanna , Spacone Antonella , Napolitano Giorgio , Parruti Giustino

Background: The coronavirus disease 2019 (COVID-19) can involve multiple organs and systems, including the endocrine system. In particular, thyroid dysfunctions are frequently seen in COVID-19 patients. The aim of this study was to evaluate thyroid function in hospitalized COVID-19 patients and to correlate thyroid function with inflammatory status, blood count parameters and mortality.Materials and methods: Data of COVID-19 patients admitted to the hosp...

ea0016p816 | Thyroid | ECE2008

Thyroid autoimmunity and assisted reproductive technology (ART)

Bucci Ines , Guglielmi Marianna , De Vita Maria Grazia , Di Nenno Barbara , Errone Dominique , Giuliani Cesidio , Napolitano Giorgio , Tiboni Giammario , Monaco Fabrizio

About 5–10% of fertile women have anti-thyroid antibodies (AAT); however this prevalence is higher in infertile women. Few studies have been focused so far on the role of thyroid autoimmunity in the outcome of ART. Aims of our studies have therefore been: a) evaluate prevalence of thyroid antibodies in infertile women before ART; b) investigate whether AAT are more prevalent in a specific subset of infertile women; c) investigate the possible influence of AAT or thyroid d...